The Australian Senator Gerard Rennick asked Pfizer executives why the vaccine against COVID-19 causes damage to the heart, without getting a clear answer
Such mechanism has been described for the first time in the letter to the editor of the Scandinavian Journal of Immunology, published on March 17th, 2022
During a hearing in the Australian Senate on August 3rd, 2023, Senator Gerard Rennick asked Pfizer executives to describe the mechanism by which the vaccine against COVID-19 causes myocarditis and pericarditis. Specifically, he repeatedly asked the executives questions such as “Can you explain the process why the vaccine is causing myocarditis and pericarditis?”, “Can you explain why the vaccines causes myocarditis?”, “Do you understand the biochemical pathway as to why the vaccine causes damage to the heart?”, without receiving a clear answer. After asking “Do you not understand the mechanism of why the vaccine causes myocarditis?”, he correctly commented “It looks to me that you don’t; and if you don’t understand it, then how you saying that the vaccine is safe without qualifying the risks?”.
https://twitter.com/SaiKate108/status/1687020049734017024
Such mechanism has been described for the first time in my letter to the editor of the Scandinavian Journal of Immunology, published on March 17th, 2022 (1).
https://twitter.com/P_McCulloughMD/status/1506340176695599104?s=20
I hypothesized such autoimmune inflammatory mechanism on the basis of the well known principles of the antigen presenting process (2). My letter's conclusion reads as follows:
“In conclusion, it is essential to underline that every human cell that intakes the LNPs and translates the viral protein (in case of the mRNA vaccines), or that gets infected by the adenovirus and expresses and translates the viral protein (in case of the adenovirus-based vaccines), is inevitably recognized as a threat by the immune system and killed (Figure 1). There are no exceptions to this mechanism. The severity of the resulting damage and the consequences for health depend on the quantity of the cells involved, on the type of tissue and on the strength of the following autoimmune reaction. For instance, if the mRNA contained in the LNPs would get internalized by cardiac myocytes, and such cells would produce the spike protein, the resulting inflammation would likely lead to the necrosis of the myocardium, with an extent proportional to the number of involved cells. Therefore, it is fundamental to perform pharmacokinetic evaluations in humans, in order to determine the exact biodistribution of the vaccines against COVID-19, and thus to identify the possible tissues at threat.”
Such biodistribution assessments have not yet been done.
Unfortunately, my original hypothesis is being confirmed over time by the histopathological findings from biopsies and autopsies done on vaccine-injured patients. In the article “Case Report: Multifocal Necrotizing Encephalitis and Myocarditis after BNT162b2 mRNA Vaccination against COVID-19” (4), Dr. Michael Mörz showed that the vaccine-derived spike protein has been synthesized in the brain and in the heart (Figure 1) of a patient, triggering lymphocytic infiltration and autoimmune inflammation.
Figure 1: Immunohistochemical image showing the vaccine-derived spike protein (brown granules) synthesized by cardiac endothelial cells of a capillary channel in the left ventricle of the heart (taken and modified from Mörz, Vaccines 2022, 10, 1651).
A similar pattern was observed in several other histopathological studies, which are listed in the review “Autoimmune Inflammatory Reactions Triggered by the COVID-19 Genetic Vaccines in Terminally Differentiated Tissues” that I co-authored with Dr. McCullough (
) and an international team of medical professionals and researchers in order to evaluate the evidence-based critical issue of the synthesis of spike protein in off-target tissues, and to explore the potential implications (5).I find it hard to comprehend how the international scientific community has not considered the consequences of the autoimmune reaction against human cells synthesizing non-self proteins as one of the major drawbacks of the genetic vaccines.
The entire hearing can be watched here (5): www.aph.gov.au/News_and_Events/Watch_Read_Listen/ParlView/video/1585181
References
1. P. Polykretis, Role of the antigen presentation process in the immunization mechanism of the genetic vaccines against COVID-19 and the need for biodistribution evaluations. Scandinavian Journal of Immunology. 96, e13160 (2022).
2. F. Kotsias, I. Cebrian, A. Alloatti, Antigen processing and presentation. Int Rev Cell Mol Biol. 348, 69–121 (2019).
3. M. Mörz, A Case Report: Multifocal Necrotizing Encephalitis and Myocarditis after BNT162b2 mRNA Vaccination against COVID-19. Vaccines. 10, 1651 (2022).
4. P. Polykretis, A. Donzelli, J. C. Lindsay, D. Wiseman, A. M. Kyriakopoulos, M. Mörz, P. Bellavite, M. Fukushima, S. Seneff, P. A. McCullough, Autoimmune Inflammatory Reactions Triggered by the COVID-19 Genetic Vaccines in Terminally Differentiated Tissues (2023), , doi:10.20944/preprints202303.0140.v1.
5. Senate Education and Employment Committee: Official Recording of Senate Committee Proceedings from the Australian Parliament (2023), (available at https://www.aph.gov.au/News_and_Events/Watch_Read_Listen/ParlView/video/1585181).